Across TCGA patient cohorts, SERPINB13 mutation is significantly associated with the RNA expression of many other genes, with 2,680 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SERPINB13-associated genes across cancer lineages are RNU6-364P, RNU1-80P, and GPX4. Each is linked with SERPINB13 in more than 2 cancer types. Because this analysis shows association rather than direction, both SERPINB13-to-partner and partner-to-SERPINB13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB13→partner) and Y-score (partner→SERPINB13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-364P →	+0.606	+7.924	<.001	.008	3	3
STAD	RNU1-80P →	+0.538	+4.085	.001	<.001	3	3
SKCM	GPX4 →	+0.465	+2.328	<.001	.003	3	2
SKCM	UQCRH →	+0.447	+2.328	.004	.003	3	2
LIHC	SNORD37 →	+0.556	+3.317	<.001	.008	3	2
SKCM	RNU6-906P →	+0.135	+2.706	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,680 associations by consensus.

Exploration

SERPINB13 survival (RNA) · tumor vs normal (RNA) · all SERPINB13 data types