SERPINB13

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SERPINB13 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SERPINB13-associated genes across cancer lineages are OR2M5, CD300H, and OR10H5. Each is linked with SERPINB13 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERPINB13-to-partner and partner-to-SERPINB13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB13→partner) and Y-score (partner→SERPINB13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOR2M5 →+0.016+4.415<.001.00731
LARGE_INTESTINECD300H →+0.033+4.415<.001.00731
BLOOD_LeukemiaOR10H5 →+0.139+4.922<.001.00931
SKINCABS1 →+0.046+5.415<.001.00431
SKINODF4 →+0.024+4.977<.001.00731
SKINKRTAP10-1 →+0.019+4.977<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration