Across TCGA pan-cancer cohorts, SERPINB11 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SERPINB11 data layer compared with 16 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher SERPINB11 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SERPINB11 expression acts as an unfavorable survival marker.

SCLC and ACC are the cancer types where SERPINB11 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Median	All	0.082	0.708	<.001	12	view →
ACC	OS	Median	All	0.118	0.624	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: SERPINB11 tumor-vs-normal RNA expression · all SERPINB11 data types