SERPINB11

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SERPINB11 mutation is significantly associated with the RNA expression of many other genes, with 1,408 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SERPINB11-associated genes across cancer lineages are RNU6-296P, RNA5SP394, and VCY. Each is linked with SERPINB11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERPINB11-to-partner and partner-to-SERPINB11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB11→partner) and Y-score (partner→SERPINB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCRNU6-296P →+0.273+4.559<.001.00632
BLCARNA5SP394 →+0.439+5.251<.001.00632
BRCAVCY →+0.064+8.471<.001.00532
BRCAMIR519E →+0.337+8.055<.001.00732
SKCMTIMM44 →+0.235+2.510.008.00932
SKCMUBE2S →+0.385+1.555.004.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,408 associations by consensus.

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