Across TCGA patient cohorts, SERPINB11 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SERPINB11-associated genes across cancer lineages are SETD2, Cyclin-E2, and Annexin-1. Each is linked with SERPINB11 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERPINB11-to-partner and partner-to-SERPINB11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINB11→partner) and Y-score (partner→SERPINB11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SETD2 →	-0.101	-1.514	.038	.014	3	2
SKCM	Cyclin-E2 →	+0.114	+1.874	.042	.047	3	2
UCEC	Annexin-1 →	+0.491	+3.019	.045	.019	3	1
UCEC	SCD →	+0.107	+2.598	.036	.006	3	1
UCEC	VHL →	-1.088	-2.459	<.001	.019	3	1
UCEC	ASNS →	+0.439	+3.000	.009	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

SERPINB11 survival (RNA) · tumor vs normal (RNA) · all SERPINB11 data types