Across TCGA patient cohorts, SERPINA5 protein abundance is significantly associated with the RNA expression of many other genes, with 16,486 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SERPINA5-associated genes across cancer lineages are C7, LMOD1, and IGFBP7. Each is linked with SERPINA5 in more than 8 cancer types. Because this analysis shows association rather than direction, both SERPINA5-to-partner and partner-to-SERPINA5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA5→partner) and Y-score (partner→SERPINA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	C7 →	+1.652	+0.583	<.001	<.001	3	9
OV	LMOD1 →	+1.613	+1.101	<.001	<.001	3	9
GBM	IGFBP7 →	+0.894	+0.513	.001	.001	3	9
BRCA	MGP →	+1.902	+0.545	<.001	<.001	3	8
UCEC	RHOJ →	+0.817	+0.919	.001	.001	3	8
OV	RBMS3 →	+0.848	+0.923	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,486 associations by consensus.

Exploration

SERPINA5 survival (RNA) · tumor vs normal (RNA) · all SERPINA5 data types