SERPINA4

Across TCGA patient cohorts, SERPINA4 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,235 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SERPINA4-associated proteins across cancer lineages are HKDC1, MYO5B, and PBLD. Each is linked with SERPINA4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SERPINA4-to-partner and partner-to-SERPINA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINA4 versus HKDC1 in LUAD, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA4→partner) and Y-score (partner→SERPINA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	HKDC1 →	+0.890	+1.184	<.001	.002	3	4
LUAD	MYO5B →	+0.351	+1.151	.006	.003	3	3
LUAD	PBLD →	+0.734	+1.326	.001	<.001	3	3
PDAC	REEP4_S152 →	-0.602	-1.046	<.001	<.001	3	3
BRCA	SHROOM2 →	+0.511	+0.292	<.001	.007	3	3
BRCA	SHROOM2_S779 →	+0.811	+0.327	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,235 associations by consensus.

SERPINA4 vs HKDC1 — LUAD

Explore this scatter interactively →