SERPINA4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SERPINA4 protein abundance is significantly associated with the RNA expression of many other genes, with 13,513 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SERPINA4-associated genes across cancer lineages are LTBP2, CNRIP1, and RECK. Each is linked with SERPINA4 in more than 8 cancer types. Because this analysis shows association rather than direction, both SERPINA4-to-partner and partner-to-SERPINA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERPINA4 versus LTBP2 in CCRCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA4→partner) and Y-score (partner→SERPINA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCLTBP2 →+1.043+0.510<.001<.00139
UCECCNRIP1 →+0.944+0.529<.001<.00139
BRCARECK →+0.847+0.566<.001<.00139
OVCALD1 →+1.110+0.783<.001<.00139
GBMCD93 →+0.995+0.668<.001<.00139
CCRCCABCA8 →+1.051+0.768<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,513 associations by consensus.

SERPINA4 vs LTBP2 — CCRCC

Per-sample scatter of SERPINA4 vs LTBP2 in CCRCC (Pearson r = 0.47).

Explore this scatter interactively →

Exploration