SERPINA4

Across TCGA cell cohorts, SERPINA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 744 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible SERPINA4-associated GO terms across cancer lineages are Lipid hydroxylation, Regulation of glial cell differentiation, and Xenobiotic export from cell. Each is linked with SERPINA4 in more than 4 cancer types. Because this analysis shows association rather than direction, both SERPINA4-to-partner and partner-to-SERPINA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipid hydroxylation grouped by SERPINA4-low versus SERPINA4-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA4→partner) and Y-score (partner→SERPINA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Lipid hydroxylation →	+1.519	+1.013	<.001	.005	2	5
LARGE_INTESTINE	Regulation of glial cell differentiation →	+0.090	+0.812	<.001	.002	3	4
LIVER	Xenobiotic export from cell →	+0.174	+1.869	<.001	<.001	3	4
LIVER	Fructose catabolic process →	+0.360	+3.154	<.001	<.001	3	4
LIVER	Fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate →	+0.360	+3.154	<.001	<.001	3	4
LIVER	Regulation of lamellipodium morphogenesis →	+0.093	+1.641	.002	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 744 associations by consensus.

Lipid hydroxylation by SERPINA4 expression — LIVER

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