Across TCGA patient cohorts, SERPINA3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,660 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SERPINA3-associated proteins across cancer lineages are EZH2_T367, NUCB1, and MMP9. Each is linked with SERPINA3 in more than 4 cancer types. Because this analysis shows association rather than direction, both SERPINA3-to-partner and partner-to-SERPINA3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA3→partner) and Y-score (partner→SERPINA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EZH2_T367 →	-0.823	-0.717	<.001	<.001	3	5
LSCC	NUCB1 →	+0.213	+0.872	.002	<.001	3	4
PDAC	MMP9 →	+0.818	+1.032	.001	.001	3	4
PDAC	NRF1 →	-0.313	-1.022	<.001	<.001	3	4
PDAC	ELAVL1 →	-0.223	-0.904	.002	.001	3	4
PDAC	PADI4 →	+0.607	+1.039	.008	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,660 associations by consensus.

Exploration

SERPINA3 survival (RNA) · tumor vs normal (RNA) · all SERPINA3 data types