Across TCGA cell cohorts, SERPINA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,406 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SERPINA3-associated GO terms across cancer lineages are Protein deglycosylation, Endoplasmic reticulum mannose trimming, and Negative regulation of multicellular organism growth. Each is linked with SERPINA3 in more than 7 cancer types. Because this analysis shows association rather than direction, both SERPINA3-to-partner and partner-to-SERPINA3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERPINA3→partner) and Y-score (partner→SERPINA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Protein deglycosylation →	+0.079	+2.105	.003	.005	3	8
OESOPHAGUS	Endoplasmic reticulum mannose trimming →	+0.173	+2.687	<.001	.007	3	7
URINARY_TRACT	Negative regulation of multicellular organism growth →	+0.188	+1.176	.002	.003	3	6
BONE	Regulation of protein exit from endoplasmic reticulum →	+0.168	+1.083	<.001	.009	3	6
SKIN	Sensory perception of mechanical stimulus →	-0.065	-4.265	.001	<.001	3	6
LUNG_NSCLC_LUAD	Regulation of hippocampal neuron apoptotic process →	+1.103	+1.112	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,406 associations by consensus.

Exploration

SERPINA3 survival (RNA) · tumor vs normal (RNA) · all SERPINA3 data types