Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, SERPINA1 mutation is significantly associated with the RNA expression of many other genes, with 912 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible SERPINA1-associated genes across cancer lineages are LSS, CHAF1A, and CHRNA5. Each is linked with SERPINA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERPINA1-to-partner and partner-to-SERPINA1 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (SERPINA1→partner) and Y-score (partner→SERPINA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.