SERP2

Across TCGA patient cohorts, SERP2 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SERP2-associated genes across cancer lineages are RNU6-591P, FAM197Y1, and FAM41AY1. Each is linked with SERP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SERP2-to-partner and partner-to-SERP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-591P grouped by SERP2-low versus SERP2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERP2→partner) and Y-score (partner→SERP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-591P →	+0.373	+7.741	<.001	.009	3	1
COAD	FAM197Y1 →	+0.064	+7.741	<.001	.009	3	1
COAD	FAM41AY1 →	+0.054	+7.741	<.001	.009	3	1
COAD	MIR5689 →	+0.468	+7.741	<.001	.009	3	1
UCEC	CTHRC1P1 →	+0.176	+4.694	.004	.007	3	1
LUAD	RNA5SP204 →	+0.789	+7.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

RNU6-591P by SERP2 expression — COAD

Explore this box plot interactively →