SERF1AP1

Across TCGA patient cohorts, SERF1AP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,231 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SERF1AP1-associated GO terms across cancer lineages are Regulation of postsynapse organization, Peptidyl-lysine dimethylation, and Regulation of DNA duplex unwinding. Each is linked with SERF1AP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SERF1AP1-to-partner and partner-to-SERF1AP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of postsynapse organization grouped by SERF1AP1-low versus SERF1AP1-high in COAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERF1AP1→partner) and Y-score (partner→SERF1AP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Regulation of postsynapse organization →	+0.055	+0.028	<.001	.001	1	4
STAD	Peptidyl-lysine dimethylation →	+0.064	+0.044	<.001	.002	3	2
UCEC	Regulation of DNA duplex unwinding →	+0.063	+0.049	<.001	.001	3	2
STAD	Columnar/cuboidal epithelial cell maturation →	+0.048	+0.044	<.001	.003	3	2
STAD	Regulation of receptor internalization →	+0.065	+0.049	<.001	<.001	3	2
STAD	Plasma cell differentiation →	+0.073	+0.039	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,231 associations by consensus.

Regulation of postsynapse organization by SERF1AP1 expression — COAD

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