SERF1AP1

Across TCGA pan-cancer cohorts, SERF1AP1 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated SERF1AP1 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher SERF1AP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SERF1AP1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

BRCA, THCA, and DLBC are the cancer types where SERF1AP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Tertile	All	0.556	0.904	<.001	102	view →
THCA	OS	Tertile	All	0.952	0.993	<.001	54	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
COAD	OS	Tertile	III,IV	0.140	0.783	.001	36	view →
READ	OS	Tertile	All	0.528	0.932	.029	36	view →
UCEC	OS	Tertile	II,III,IV	1.000	0.466	.033	24	view →
LAML	DFS	Tertile	All	0.181	0.574	.048	18	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

SERF1AP1–BRCA (DFS)

Open the BRCA breakdown →