SERBP1

Across TCGA patient cohorts, SERBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,237 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SERBP1-associated genes across cancer lineages are KLF2, TMEM119, and LINC00702. Each is linked with SERBP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SERBP1-to-partner and partner-to-SERBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SERBP1 versus KLF2 in LSCC, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SERBP1→partner) and Y-score (partner→SERBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KLF2 →	-0.753	-0.146	<.001	<.001	3	8
OV	TMEM119 →	-1.287	-0.292	.001	<.001	3	8
HNSC	LINC00702 →	-0.744	-0.184	.001	.009	3	8
OV	IFFO1 →	-1.019	-0.397	<.001	<.001	3	8
UCEC	ABCA8 →	-1.365	-0.215	<.001	<.001	3	8
UCEC	PTH1R →	-0.870	-0.185	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,237 associations by consensus.

SERBP1 vs KLF2 — LSCC

Explore this scatter interactively →