SERAC1

Across TCGA cell cohorts, SERAC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,115 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SERAC1-associated GO terms across cancer lineages are Phosphatidylinositol biosynthetic process, Post-Golgi vesicle-mediated transport, and Phosphatidylinositol metabolic process. Each is linked with SERAC1 in more than 15 cancer types. Because this analysis shows association rather than direction, both SERAC1-to-partner and partner-to-SERAC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Phosphatidylinositol biosynthetic process grouped by SERAC1-low versus SERAC1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SERAC1→partner) and Y-score (partner→SERAC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Phosphatidylinositol biosynthetic process →	+0.066	+1.113	.001	<.001	3	16
LUNG_NSCLC_LUSC	Post-Golgi vesicle-mediated transport →	+0.064	+0.938	.001	<.001	3	15
LUNG_NSCLC_LUSC	Phosphatidylinositol metabolic process →	+0.066	+0.865	<.001	.003	2	15
LUNG_NSCLC_LUSC	Golgi to plasma membrane transport →	+0.086	+1.007	<.001	<.001	3	13
BONE	Vesicle-mediated transport to the plasma membrane →	+0.056	+0.684	<.001	.005	3	13
BONE	Golgi vesicle transport →	+0.059	+1.291	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,115 associations by consensus.

Phosphatidylinositol biosynthetic process by SERAC1 expression — URINARY_TRACT

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