SEPTIN8

Across TCGA patient cohorts, SEPTIN8 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,948 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SEPTIN8-associated proteins across cancer lineages are PALLD, PDLIM7, and VCAN. Each is linked with SEPTIN8 in more than 5 cancer types. Because this analysis shows association rather than direction, both SEPTIN8-to-partner and partner-to-SEPTIN8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEPTIN8 versus PALLD in OV, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN8→partner) and Y-score (partner→SEPTIN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PALLD →	+0.820	+1.019	<.001	<.001	3	6
OV	PDLIM7 →	+0.581	+0.839	<.001	<.001	3	6
OV	VCAN →	+1.187	+0.727	<.001	<.001	3	6
OV	CNN3 →	+0.572	+0.732	<.001	<.001	3	6
LSCC	RASA1 →	+0.257	+0.435	<.001	<.001	3	5
BRCA	OMD →	+1.277	+0.725	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,948 associations by consensus.

SEPTIN8 vs PALLD — OV

Explore this scatter interactively →