SEPTIN8

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SEPTIN8 protein abundance is significantly associated with the protein abundance of many other proteins, with 26,713 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible SEPTIN8-associated proteins across cancer lineages are SEPTIN2, SEPTIN7, and LUM. Each is linked with SEPTIN8 in more than 9 cancer types. Because this analysis shows association rather than direction, both SEPTIN8-to-partner and partner-to-SEPTIN8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEPTIN8 versus SEPTIN2 in PDAC, with a Pearson correlation of 0.77.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN8→partner) and Y-score (partner→SEPTIN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACSEPTIN2 →+0.363+0.389<.001<.001310
PDACSEPTIN7 →+0.359+0.414<.001<.001310
OVLUM →+1.020+0.455<.001.00139
PDACMYL6 →+0.392+0.292<.001<.00139
CCRCCPDLIM5 →+0.748+0.292<.001<.00139
GBMPTPN2_S304 →-0.646-0.531<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 26,713 associations by consensus.

SEPTIN8 vs SEPTIN2 — PDAC

Per-sample scatter of SEPTIN8 vs SEPTIN2 in PDAC (Pearson r = 0.77).

Explore this scatter interactively →

Exploration