SEPTIN8

Across TCGA cell cohorts, SEPTIN8 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,731 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SEPTIN8-associated GO terms across cancer lineages are Golgi vesicle transport, Regulation of intracellular transport, and Cytoskeleton-dependent cytokinesis. Each is linked with SEPTIN8 in more than 12 cancer types. Because this analysis shows association rather than direction, both SEPTIN8-to-partner and partner-to-SEPTIN8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by SEPTIN8-low versus SEPTIN8-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN8→partner) and Y-score (partner→SEPTIN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Golgi vesicle transport →	+0.053	+1.112	<.001	<.001	3	13
SKIN	Regulation of intracellular transport →	+0.061	+0.898	<.001	<.001	3	12
BREAST	Cytoskeleton-dependent cytokinesis →	+0.074	+1.259	.001	<.001	2	13
BREAST	Cytokinesis →	+0.066	+0.923	.001	<.001	2	13
OESOPHAGUS	Vesicle-mediated transport to the plasma membrane →	+0.084	+0.677	.001	.009	2	12
OESOPHAGUS	Cytosolic transport →	+0.073	+0.903	.006	.001	1	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,731 associations by consensus.

Golgi vesicle transport by SEPTIN8 expression — BREAST

Explore this box plot interactively →