SEPTIN7P6

Across TCGA pan-cancer cohorts, SEPTIN7P6 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated SEPTIN7P6 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SEPTIN7P6 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SEPTIN7P6 expression acts as an unfavorable survival marker, although some lineages such as SKCM and LAML show a favorable association.

ACC, SKCM, and MESO are the cancer types where SEPTIN7P6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.490	0.795	<.001	76	view →
SKCM	OS	Tertile	III,IV	0.530	0.233	<.001	51	view →
MESO	OS	Tertile	All	0.408	0.665	<.001	49	view →
LGG	DFS	Median	All	0.659	0.818	<.001	45	view →
UVM	OS	Quartile	III,IV	0.377	0.806	.001	40	view →
LAML	DFS	Tertile	All	0.730	0.394	.007	36	view →
CESC	OS	Quartile	III,IV	0.304	0.699	.014	36	view →
LUSC	OS	Tertile	II,III,IV	0.457	0.275	.011	17	view →
READ	OS	Tertile	IV	0.487	0.913	.003	17	view →
GBM	DFS	Quartile	All	0.430	0.168	.016	9	view →
UCS	DFS	Median	IV	0.835	0.490	.031	6	view →
ESCA	DFS	Tertile	III,IV	0.433	0.243	.029	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

SEPTIN7P6–ACC (DFS)

Open the ACC breakdown →