SEPTIN7P6

Across TCGA pan-cancer cohorts, SEPTIN7P6 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SEPTIN7P6’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where SEPTIN7P6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SEPTIN7P6 is over-expressed in tumor.

COAD, BRCA, and HNSC are the cancer types where SEPTIN7P6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SEPTIN7P6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	+0.207	.003	5	view →
BRCA	All	All	+0.166	.029	4	view →
HNSC	All	II,III,IV	+0.063	.003	4	view →
KIRC	All	All	+0.039	.004	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

SEPTIN7P6–COAD

Open the COAD breakdown →