SEPTIN7P13

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SEPTIN7P13 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SEPTIN7P13-associated genes across cancer lineages are MIR6859-2, TBC1D3L, and HNRNPCL3. Each is linked with SEPTIN7P13 in more than 1 cancer types. Because this analysis shows association rather than direction, both SEPTIN7P13-to-partner and partner-to-SEPTIN7P13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN7P13→partner) and Y-score (partner→SEPTIN7P13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR6859-2 →+0.903+5.427<.001<.00131
UCECTBC1D3L →+0.800+3.626<.001.00831
UCECHNRNPCL3 →+0.051+4.193.008.00131
UCECPMS2P6 →+0.448+3.818<.001.00531
UCECHMX3 →+1.204+3.859<.001.00431
UCECRNU6-222P →+0.910+4.224<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

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