SEPTIN6

Across TCGA patient cohorts, SEPTIN6 protein abundance is significantly associated with the RNA expression of many other genes, with 16,579 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SEPTIN6-associated genes across cancer lineages are EBI3, ZNF831, and TESPA1. Each is linked with SEPTIN6 in more than 9 cancer types. Because this analysis shows association rather than direction, both SEPTIN6-to-partner and partner-to-SEPTIN6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEPTIN6 versus EBI3 in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN6→partner) and Y-score (partner→SEPTIN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EBI3 →	+0.812	+0.503	.002	<.001	3	10
HNSC	ZNF831 →	+0.998	+0.535	<.001	<.001	3	10
CCRCC	TESPA1 →	+0.955	+0.404	<.001	<.001	3	10
LSCC	STAT4 →	+0.856	+0.460	<.001	<.001	3	10
CCRCC	CD8A →	+1.368	+0.301	<.001	<.001	3	10
HNSC	THEMIS →	+1.175	+0.453	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,579 associations by consensus.

SEPTIN6 vs EBI3 — OV

Explore this scatter interactively →