Across TCGA patient cohorts, SEPTIN5 protein abundance is significantly associated with the RNA expression of many other genes, with 6,360 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SEPTIN5-associated genes across cancer lineages are LINC02446, CPXM2, and ATP8A2. Each is linked with SEPTIN5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SEPTIN5-to-partner and partner-to-SEPTIN5 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN5→partner) and Y-score (partner→SEPTIN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC02446 →	-2.006	-0.919	.004	.004	3	3
LSCC	CPXM2 →	+1.817	+0.751	<.001	.009	3	3
GBM	ATP8A2 →	+2.440	+1.538	<.001	.002	3	3
BRCA	RERG →	+1.762	+0.756	.001	<.001	3	3
COAD	ARMH4 →	+0.833	+0.714	<.001	<.001	3	3
BRCA	ANKRD50 →	+0.693	+0.450	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,360 associations by consensus.

Exploration

SEPTIN5 survival (RNA) · tumor vs normal (RNA) · all SEPTIN5 data types