SEPTIN5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SEPTIN5 mutation is significantly associated with the RNA expression of many other genes, with 1,123 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SEPTIN5-associated genes across cancer lineages are MIR181A1, LINC02446, and WRBP1. Each is linked with SEPTIN5 in more than 2 cancer types. Because this analysis shows association rather than direction, both SEPTIN5-to-partner and partner-to-SEPTIN5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN5→partner) and Y-score (partner→SEPTIN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAMIR181A1 →+0.184+4.859<.001.00433
UCECLINC02446 →+0.984+3.258<.001<.00133
CESCWRBP1 →+0.277+4.234<.001.00832
CESCOR5AC4P →+0.030+5.569<.001.00232
CESCRNA5SP325 →+0.241+5.837<.001.00132
UCECCDKN3 →+0.645+3.459.005.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,123 associations by consensus.

Exploration