Across TCGA patient cohorts, SEPTIN10 protein abundance is significantly associated with the RNA expression of many other genes, with 12,881 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SEPTIN10-associated genes across cancer lineages are MTURN, MAMDC2, and AHNAK. Each is linked with SEPTIN10 in more than 5 cancer types. Because this analysis shows association rather than direction, both SEPTIN10-to-partner and partner-to-SEPTIN10 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN10→partner) and Y-score (partner→SEPTIN10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MTURN →	+1.190	+0.273	<.001	.005	3	6
UCEC	MAMDC2 →	+1.070	+0.259	<.001	<.001	3	6
GBM	AHNAK →	+0.779	+0.309	<.001	<.001	3	6
OV	URGCP →	+0.394	+0.373	.003	.008	2	6
LUAD	LMNB1 →	-0.846	-0.244	<.001	<.001	3	5
LSCC	NUDCD3 →	+0.418	+0.303	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,881 associations by consensus.

Exploration

SEPTIN10 survival (RNA) · tumor vs normal (RNA) · all SEPTIN10 data types