SEPTIN1

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SEPTIN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,044 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SEPTIN1-associated proteins across cancer lineages are RCSD1, ANKRD44, and LAT_S224. Each is linked with SEPTIN1 in more than 8 cancer types. Because this analysis shows association rather than direction, both SEPTIN1-to-partner and partner-to-SEPTIN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEPTIN1 versus RCSD1 in HNSC, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEPTIN1→partner) and Y-score (partner→SEPTIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRCSD1 →+0.594+0.826<.001<.00139
HNSCANKRD44 →+0.509+1.055<.001<.00139
LUADLAT_S224 →+1.047+0.673<.001<.00139
HNSCLCP1 →+0.570+0.871<.001<.00139
HNSCLCP2 →+0.551+0.813<.001<.00139
OVLIMD2 →+0.831+0.609.002.00239
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,044 associations by consensus.

SEPTIN1 vs RCSD1 — HNSC

Per-sample scatter of SEPTIN1 vs RCSD1 in HNSC (Pearson r = 0.50).

Explore this scatter interactively →

Exploration