SEMG2

Across TCGA patient cohorts, SEMG2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,682 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible SEMG2-associated GO terms across cancer lineages are Polyol metabolic process, DGMP metabolic process, and Cardiac muscle cell-cardiac muscle cell adhesion. Each is linked with SEMG2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SEMG2-to-partner and partner-to-SEMG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Polyol metabolic process grouped by SEMG2-low versus SEMG2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMG2→partner) and Y-score (partner→SEMG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Polyol metabolic process →	+0.031	+0.322	<.001	<.001	3	5
ESCA	DGMP metabolic process →	+0.078	+0.371	<.001	.002	3	5
STAD	Cardiac muscle cell-cardiac muscle cell adhesion →	+0.080	+0.279	<.001	<.001	3	4
GBM	Postsynaptic modulation of chemical synaptic transmission →	+0.060	+0.013	<.001	.001	3	4
ESCA	Regulation of microvillus organization →	+0.060	+0.287	<.001	<.001	3	4
STAD	Oligopeptide transmembrane transport →	+0.088	+0.557	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,682 associations by consensus.

Polyol metabolic process by SEMG2 expression — ESCA

Explore this box plot interactively →