SEMA7A

Across TCGA patient cohorts, SEMA7A RNA expression is significantly associated with the protein abundance of many other proteins, with 18,060 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SEMA7A-associated proteins across cancer lineages are PPP1R18, PLAU, and MAP7D1. Each is linked with SEMA7A in more than 7 cancer types. Because this analysis shows association rather than direction, both SEMA7A-to-partner and partner-to-SEMA7A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEMA7A versus PPP1R18 in OV, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA7A→partner) and Y-score (partner→SEMA7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PPP1R18 →	+0.385	+0.740	<.001	<.001	3	8
CCRCC	PLAU →	+0.777	+0.669	.002	.008	3	8
HNSC	MAP7D1 →	+0.375	+0.617	<.001	<.001	3	8
OV	WAS →	+0.412	+0.984	.004	<.001	3	7
OV	P4HA2 →	+0.649	+0.851	<.001	<.001	3	7
BRCA	SH3KBP1 →	+0.568	+0.837	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,060 associations by consensus.

SEMA7A vs PPP1R18 — OV

Explore this scatter interactively →