SEMA7A

Across TCGA cell cohorts, SEMA7A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,036 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SEMA7A-associated GO terms across cancer lineages are Ameboidal-type cell migration, Regulation of protein maturation, and Regulation of protein processing. Each is linked with SEMA7A in more than 14 cancer types. Because this analysis shows association rather than direction, both SEMA7A-to-partner and partner-to-SEMA7A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ameboidal-type cell migration grouped by SEMA7A-low versus SEMA7A-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA7A→partner) and Y-score (partner→SEMA7A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Ameboidal-type cell migration →	+0.086	+2.148	<.001	<.001	3	15
BONE	Regulation of protein maturation →	+0.171	+2.359	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Regulation of protein processing →	+0.176	+2.852	.001	.001	3	15
BONE	Viral life cycle →	+0.091	+2.524	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Urokinase plasminogen activator signaling pathway →	+0.921	+3.163	.001	<.001	3	14
BONE	Wound healing →	+0.128	+2.788	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,036 associations by consensus.

Ameboidal-type cell migration by SEMA7A expression — LARGE_INTESTINE

Explore this box plot interactively →