SEMA6B

Across TCGA patient cohorts, SEMA6B protein abundance is significantly associated with the RNA expression of many other genes, with 2,211 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SEMA6B-associated genes across cancer lineages are PCAT19, MXI1, and SCARNA18. Each is linked with SEMA6B in more than 2 cancer types. Because this analysis shows association rather than direction, both SEMA6B-to-partner and partner-to-SEMA6B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEMA6B versus PCAT19 in LUAD, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA6B→partner) and Y-score (partner→SEMA6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PCAT19 →	+0.695	+0.747	.008	.003	3	3
BRCA	MXI1 →	-0.958	-0.296	.006	.007	3	2
BRCA	SCARNA18 →	-1.001	-0.393	.009	<.001	3	2
LUAD	MIR30B →	-1.739	-0.801	.003	.003	3	2
LUAD	RNU6-1118P →	-0.667	-0.668	.001	.001	3	2
CCRCC	GNG11 →	+0.934	+0.733	.009	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,211 associations by consensus.

SEMA6B vs PCAT19 — LUAD

Explore this scatter interactively →