SEMA6B

Across TCGA cell cohorts, SEMA6B RNA expression is significantly associated with the RNA expression of many other genes, with 10,359 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SEMA6B-associated genes across cancer lineages are GPSM1, SMARCD3, and NLGN2. Each is linked with SEMA6B in more than 11 cancer types. Because this analysis shows association rather than direction, both SEMA6B-to-partner and partner-to-SEMA6B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEMA6B versus GPSM1 in LARGE_INTESTINE, with a Pearson correlation of 0.44.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA6B→partner) and Y-score (partner→SEMA6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GPSM1 →	+1.943	+1.072	<.001	<.001	3	12
LUNG_SCLC	SMARCD3 →	+2.074	+2.256	<.001	.001	3	12
STOMACH	NLGN2 →	+1.993	+2.130	<.001	<.001	3	11
OVARY	C1QL4 →	+1.797	+2.194	<.001	<.001	3	10
URINARY_TRACT	MAP3K12 →	+2.315	+2.732	<.001	<.001	3	10
LUNG_SCLC	DIRAS1 →	+2.884	+2.615	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,359 associations by consensus.

SEMA6B vs GPSM1 — LARGE_INTESTINE

Explore this scatter interactively →