SEMA6B

Across TCGA cell cohorts, SEMA6B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,796 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SEMA6B-associated GO terms across cancer lineages are Cell communication involved in cardiac conduction, Nucleoside triphosphate metabolic process, and Thigmotaxis. Each is linked with SEMA6B in more than 11 cancer types. Because this analysis shows association rather than direction, both SEMA6B-to-partner and partner-to-SEMA6B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell communication involved in cardiac conduction grouped by SEMA6B-low versus SEMA6B-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA6B→partner) and Y-score (partner→SEMA6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cell communication involved in cardiac conduction →	-0.177	-1.615	.004	.002	3	12
PANCREAS	Nucleoside triphosphate metabolic process →	+0.081	+2.487	<.001	<.001	3	11
SKIN	Thigmotaxis →	+0.164	+1.605	.004	<.001	3	11
STOMACH	Glycolytic process through fructose-6-phosphate →	+0.128	+1.334	<.001	.007	3	11
STOMACH	Glycolytic process through glucose-6-phosphate →	+0.128	+1.334	<.001	.007	3	11
PANCREAS	ATP metabolic process →	+0.074	+1.787	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,796 associations by consensus.

Cell communication involved in cardiac conduction by SEMA6B expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →