SEMA5B

Across TCGA patient cohorts, SEMA5B protein abundance is significantly associated with the RNA expression of many other genes, with 4,356 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SEMA5B-associated genes across cancer lineages are MYBL2, AUNIP, and KIF2C. Each is linked with SEMA5B in more than 1 cancer types. Because this analysis shows association rather than direction, both SEMA5B-to-partner and partner-to-SEMA5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEMA5B versus MYBL2 in LUAD, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA5B→partner) and Y-score (partner→SEMA5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MYBL2 →	+1.383	+0.995	.007	.007	3	2
LUAD	AUNIP →	+0.899	+1.370	.003	.002	3	2
LUAD	KIF2C →	+0.973	+1.174	.008	.002	3	2
LUAD	INCENP →	+0.840	+1.405	<.001	<.001	3	2
GBM	GAREM2 →	+0.975	+0.762	.002	<.001	3	2
LUAD	CCNF →	+0.788	+1.182	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,356 associations by consensus.

SEMA5B vs MYBL2 — LUAD

Explore this scatter interactively →