SEMA5B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SEMA5B protein abundance is significantly associated with the protein abundance of many other proteins, with 7,136 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SEMA5B-associated proteins across cancer lineages are ACTR2_T117, BIN2_S458, and C1orf35_S178. Each is linked with SEMA5B in more than 1 cancer types. Because this analysis shows association rather than direction, both SEMA5B-to-partner and partner-to-SEMA5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEMA5B versus ACTR2_T117 in GBM, with a Pearson correlation of -0.39.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA5B→partner) and Y-score (partner→SEMA5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMACTR2_T117 →-0.404-0.447.001<.00132
CCRCCBIN2_S458 →-0.600-0.786<.001<.00132
CCRCCC1orf35_S178 →+0.613+0.750<.001.00132
GBMCARD16 →-0.686-0.475<.001.00132
CCRCCCDC23 →+0.171+0.754<.001<.00132
GBMDBF4_S359 →+0.799+0.676<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,136 associations by consensus.

SEMA5B vs ACTR2_T117 — GBM

Per-sample scatter of SEMA5B vs ACTR2_T117 in GBM (Pearson r = -0.39).

Explore this scatter interactively →

Exploration