SEMA3A

Across TCGA cell cohorts, SEMA3A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,194 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SEMA3A-associated GO terms across cancer lineages are Basal dendrite development, Basal dendrite morphogenesis, and Basal dendrite arborization. Each is linked with SEMA3A in more than 12 cancer types. Because this analysis shows association rather than direction, both SEMA3A-to-partner and partner-to-SEMA3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Basal dendrite development grouped by SEMA3A-low versus SEMA3A-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEMA3A→partner) and Y-score (partner→SEMA3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Basal dendrite development →	+0.200	+1.727	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Basal dendrite morphogenesis →	+0.200	+1.727	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Basal dendrite arborization →	+0.200	+1.727	<.001	<.001	3	13
LUNG_SCLC	Sympathetic neuron projection guidance →	+1.241	+2.830	<.001	<.001	3	11
LARGE_INTESTINE	Facial nerve development →	+0.477	+1.457	.001	<.001	3	11
LARGE_INTESTINE	Facial nerve morphogenesis →	+0.477	+1.457	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,194 associations by consensus.

Basal dendrite development by SEMA3A expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →