Across TCGA patient cohorts, SELENOT mutation is significantly associated with the RNA expression of many other genes, with 1,049 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SELENOT-associated genes across cancer lineages are RPSAP37, RNU6-1148P, and RNU7-8P. Each is linked with SELENOT in more than 1 cancer types. Because this analysis shows association rather than direction, both SELENOT-to-partner and partner-to-SELENOT results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOT→partner) and Y-score (partner→SELENOT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RPSAP37 →	+0.054	+5.867	<.001	.003	3	2
BLCA	RNU6-1148P →	+0.352	+7.640	<.001	.009	3	2
BLCA	RNU7-8P →	+1.032	+7.640	<.001	.009	3	2
SKCM	CCT3P1 →	+0.103	+5.097	<.001	.008	3	2
SKCM	LINC02563 →	+0.161	+5.867	<.001	.003	3	2
UCEC	OR2AP1 →	+0.045	+3.267	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,049 associations by consensus.

Exploration

SELENOT survival (RNA) · tumor vs normal (RNA) · all SELENOT data types