SELENOS

Across TCGA patient cohorts, SELENOS RNA expression is significantly associated with the mutation status of many other genes, with 11,510 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SELENOS-associated genes across cancer lineages are MUC16, TTN, and KMT2D. Each is linked with SELENOS in more than 5 cancer types. Because this analysis shows association rather than direction, both SELENOS-to-partner and partner-to-SELENOS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MUC16 grouped by SELENOS-low versus SELENOS-high in ESCA.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOS→partner) and Y-score (partner→SELENOS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	MUC16 →	+1.819	+0.280	.003	.006	2	6
UCEC	TTN →	+1.062	+0.256	<.001	<.001	3	4
SKCM	KMT2D →	+1.321	+0.229	<.001	.006	3	4
UCEC	TLL1 →	+1.908	+0.457	<.001	<.001	3	4
UCEC	COL4A4 →	+1.477	+0.315	<.001	<.001	3	4
UCEC	MYO1F →	+2.050	+0.440	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,510 associations by consensus.

MUC16 by SELENOS expression — ESCA

Explore this box plot interactively →