SELENOO

Across TCGA patient cohorts, SELENOO RNA expression is significantly associated with the protein abundance of many other proteins, with 10,599 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SELENOO-associated proteins across cancer lineages are ZBED4_S624, XRCC5, and XRCC6. Each is linked with SELENOO in more than 3 cancer types. Because this analysis shows association rather than direction, both SELENOO-to-partner and partner-to-SELENOO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SELENOO versus ZBED4_S624 in OV, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOO→partner) and Y-score (partner→SELENOO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZBED4_S624 →	+0.809	+0.809	.003	.002	3	4
GBM	XRCC5 →	+0.244	+0.325	<.001	<.001	3	3
GBM	XRCC6 →	+0.254	+0.354	<.001	<.001	3	3
LSCC	SEC24A →	-0.244	-0.391	<.001	<.001	3	3
PDAC	CDK17 →	-0.294	-0.186	<.001	.003	3	3
CCRCC	CDV3 →	-0.285	-0.318	.004	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,599 associations by consensus.

SELENOO vs ZBED4_S624 — OV

Explore this scatter interactively →