SELENOO

Across TCGA pan-cancer cohorts, SELENOO RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of SELENOO’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where SELENOO RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SELENOO is over-expressed in tumor, although a few such as KIRP and BRCA show the opposite, repressed pattern.

HNSC, KIRP, and COAD are the cancer types where SELENOO tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SELENOO RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.625	<.001	10	view →
KIRP	All	III,IV	−0.944	<.001	9	view →
COAD	Female	All	+0.793	<.001	7	view →
STAD	Male	II,III,IV	+0.652	<.001	6	view →
LUSC	Male	All	+0.657	<.001	4	view →
BRCA	Female	II,III,IV	−0.250	.014	4	view →
READ	Female	All	+0.895	<.001	2	view →
LUAD	Male	All	−0.381	.005	1	view →
KICH	All	All	−0.365	.017	1	view →
THCA	Male	III,IV	−0.304	.017	1	view →
KIRC	Male	All	−0.238	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

SELENOO–HNSC

Open the HNSC breakdown →