SELENOO

Across TCGA cell cohorts, SELENOO RNA expression is significantly associated with the go_rna of many other GO terms, with 4,517 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SELENOO-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and Meiotic chromosome condensation. Each is linked with SELENOO in more than 15 cancer types. Because this analysis shows association rather than direction, both SELENOO-to-partner and partner-to-SELENOO results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by SELENOO-low versus SELENOO-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOO→partner) and Y-score (partner→SELENOO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Symbiont-mediated disruption of host cellular anatomical structure →	+0.135	+0.816	.002	.006	3	16
UPPER_AERODIGESTIVE_TRACT	Symbiont-mediated disruption of host anatomical structure →	+0.135	+0.816	.002	.006	3	16
SKIN	Meiotic chromosome condensation →	+0.172	+1.190	<.001	<.001	3	14
BONE	DNA replication proofreading →	+0.192	+1.199	<.001	<.001	3	14
BONE	DNA topological change →	+0.138	+0.996	.001	.002	3	14
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.183	+1.143	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,517 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by SELENOO expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →