Across TCGA patient cohorts, SELENOM mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SELENOM-associated genes across cancer lineages are HSPE1-MOB4, MIR7702, and OR9Q2. Each is linked with SELENOM in more than 1 cancer types. Because this analysis shows association rather than direction, both SELENOM-to-partner and partner-to-SELENOM results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOM→partner) and Y-score (partner→SELENOM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HSPE1-MOB4 →	+0.228	+3.432	.003	.009	3	1
UCEC	MIR7702 →	+0.537	+5.738	<.001	<.001	3	1
COAD	OR9Q2 →	+0.070	+6.721	<.001	<.001	3	1
COAD	RNA5SP167 →	+0.572	+6.392	.002	.001	3	1
COAD	MIR147A →	+0.699	+5.893	<.001	.002	3	1
COAD	RNU7-11P →	+0.842	+5.145	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

SELENOM survival (RNA) · tumor vs normal (RNA) · all SELENOM data types