SELENOK

Across TCGA cell cohorts, SELENOK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,515 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SELENOK-associated GO terms across cancer lineages are tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation, Regulation of L-glutamate import across plasma membrane, and Lipid phosphorylation. Each is linked with SELENOK in more than 13 cancer types. Because this analysis shows association rather than direction, both SELENOK-to-partner and partner-to-SELENOK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation grouped by SELENOK-low versus SELENOK-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOK→partner) and Y-score (partner→SELENOK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation →	+0.142	+0.836	<.001	<.001	3	14
BONE	Regulation of L-glutamate import across plasma membrane →	+0.220	+1.172	<.001	<.001	3	10
BLOOD_Lymphoma	Lipid phosphorylation →	-0.082	-0.582	<.001	<.001	3	9
URINARY_TRACT	Protein localization to early endosome →	+0.194	+0.869	.001	.007	2	10
OVARY	Mitotic sister chromatid separation →	-0.146	-0.713	<.001	.009	3	9
LIVER	Regulation of protein exit from endoplasmic reticulum →	+0.141	+0.563	.001	.006	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,515 associations by consensus.

tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation by SELENOK expression — LARGE_INTESTINE

Explore this box plot interactively →