SELENOI

Across TCGA cell cohorts, SELENOI RNA expression is significantly associated with the go_rna of many other GO terms, with 4,821 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SELENOI-associated GO terms across cancer lineages are DNA-templated DNA replication, Regulation of mRNA catabolic process, and Regulation of centrosome duplication. Each is linked with SELENOI in more than 14 cancer types. Because this analysis shows association rather than direction, both SELENOI-to-partner and partner-to-SELENOI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication grouped by SELENOI-low versus SELENOI-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOI→partner) and Y-score (partner→SELENOI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.099	+0.796	<.001	<.001	3	15
SOFT_TISSUE	Regulation of mRNA catabolic process →	+0.066	+1.055	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of centrosome duplication →	+0.097	+1.081	<.001	<.001	3	15
BLOOD_Lymphoma	Regulation of RNA stability →	+0.067	+1.223	<.001	<.001	3	15
BLOOD_Lymphoma	DNA replication, removal of RNA primer →	+0.114	+0.871	<.001	<.001	3	15
SOFT_TISSUE	Mitotic DNA integrity checkpoint signaling →	+0.083	+1.086	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,821 associations by consensus.

DNA-templated DNA replication by SELENOI expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →