Across TCGA patient cohorts, SELENOH protein abundance is significantly associated with the RNA expression of many other genes, with 11,594 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SELENOH-associated genes across cancer lineages are CXCL8, FPR2, and SOD2. Each is linked with SELENOH in more than 5 cancer types. Because this analysis shows association rather than direction, both SELENOH-to-partner and partner-to-SELENOH results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOH→partner) and Y-score (partner→SELENOH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CXCL8 →	-1.852	-0.432	<.001	<.001	3	6
UCEC	FPR2 →	-1.039	-0.427	<.001	<.001	3	5
GBM	SOD2 →	-0.982	-0.304	<.001	<.001	3	5
CCRCC	AQP9 →	-1.369	-0.335	<.001	<.001	3	4
UCEC	VNN2 →	-1.071	-0.340	.002	.003	2	5
UCEC	NCF2 →	-1.087	-0.407	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,594 associations by consensus.

Exploration

SELENOH survival (RNA) · tumor vs normal (RNA) · all SELENOH data types