Across TCGA pan-cancer cohorts, SELENOH RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of SELENOH’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where SELENOH RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SELENOH is over-expressed in tumor.
KIRC, BLCA, and COAD are the cancer types where SELENOH tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SELENOH RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.