Across TCGA patient cohorts, SELENOH mutation is significantly associated with the RNA expression of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SELENOH-associated genes across cancer lineages are DBF4P3, RNA5SP412, and RN7SKP221. Each is linked with SELENOH in more than 1 cancer types. Because this analysis shows association rather than direction, both SELENOH-to-partner and partner-to-SELENOH results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SELENOH→partner) and Y-score (partner→SELENOH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DBF4P3 →	+0.044	+4.660	<.001	.003	3	1
UCEC	RNA5SP412 →	+0.893	+2.967	<.001	.007	3	1
BRCA	RN7SKP221 →	+0.065	+7.471	<.001	.008	3	1
BRCA	TRDD1 →	+0.910	+8.057	<.001	.005	3	1
BRCA	HSPE1P24 →	+0.187	+6.064	<.001	.002	3	1
UCEC	MIR6803 →	+0.488	+6.741	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

Exploration

SELENOH survival (RNA) · tumor vs normal (RNA) · all SELENOH data types