SEL1L2

Across TCGA patient cohorts, SEL1L2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,135 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SEL1L2-associated genes across cancer lineages are DDX17, SUN2, and DNAL4. Each is linked with SEL1L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SEL1L2-to-partner and partner-to-SEL1L2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEL1L2 versus DDX17 in PDAC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEL1L2→partner) and Y-score (partner→SEL1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	DDX17 →	+0.214	+0.569	.004	.002	3	1
PDAC	SUN2 →	+0.279	+0.520	<.001	<.001	3	1
PDAC	DNAL4 →	+0.278	+0.438	<.001	.003	3	1
PDAC	CBX7 →	+0.408	+0.804	<.001	<.001	3	1
PDAC	TAB1 →	+0.209	+0.396	<.001	.009	3	1
PDAC	GRAP2 →	+0.426	+0.492	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,135 associations by consensus.

SEL1L2 vs DDX17 — PDAC

Explore this scatter interactively →