SEL1L2

Across TCGA cell cohorts, SEL1L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 258 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SEL1L2-associated GO terms across cancer lineages are Natural killer cell mediated immunity, Follicular B cell differentiation, and Glycoprotein catabolic process. Each is linked with SEL1L2 in more than 2 cancer types. Because this analysis shows association rather than direction, both SEL1L2-to-partner and partner-to-SEL1L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Natural killer cell mediated immunity grouped by SEL1L2-low versus SEL1L2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEL1L2→partner) and Y-score (partner→SEL1L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Natural killer cell mediated immunity →	+0.110	+0.162	<.001	.007	3	3
BLOOD_Leukemia	Follicular B cell differentiation →	+0.573	+0.163	.002	.007	3	3
SKIN	Glycoprotein catabolic process →	+0.082	+0.048	<.001	.007	3	3
SKIN	Lysosomal transport →	+0.046	+0.048	<.001	.007	3	3
BLOOD_Leukemia	Positive regulation of D-glucose transmembrane transport →	+0.050	+0.158	.002	.009	3	2
BLOOD_Leukemia	Glycoside catabolic process →	+0.169	+0.168	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 258 associations by consensus.

Natural killer cell mediated immunity by SEL1L2 expression — BLOOD_Leukemia

Explore this box plot interactively →